Dear Sis,
I hope this will find you and yours healthy and happy.
I took your role in my life as my sister for granted; I didn’t know what it really meant. You annoyed me and seemed to impede what I wanted when I was in high school, but that soon gave way to an encouragement I enjoyed receiving. I am sorry we are estranged, and I wait with great hope to see you again.
The last time I saw you I was engaged to an amazing woman, and being disowned our brother and ostracized by our mother. The last time we spoke, we laughed about these twisted and distorted relationships. I’ve made good decisions and bad decisions in life, and I can’t regret the ones that have brought me to this wonderful family I am building with my amazing wife. However, I do have a choice I regret, and it is the things I said (that I didn’t quite understand) that put me in opposition to my sister… to you.
I miss you.

In the years that we have been out of contact I have been happily married, traveled to Ecuador, and Greece, became a parent twice, finished my BA and earned my MA in Special Education. I have been the best uncle I know to be, I am learning to be the best husband I can, I am trying to continue to be a good dad (our example was easily surpassed), but I have been a horrible brother.
I know sorry is too little too late, and I know I can’t unsay what’s been said or undo what’s been done. But you are my sister, and I am your brother. I hope this find you and your family in a good place.